Sensory and Neuromotor System Disorders CRO


In vivex is a preclinical Contract Research Organization ( CRO )
specialized in the evaluation of sensory and neuromotor system disorders

Pharmacokinetic studies

Pharmacokinetic studies attempt to analyze chemical metabolism and to discover the fate of a new pharmacological candidate from the moment that it is administered up to the point at which it is completely eliminated from the body. PK study is a mandatory step for the development of efficacy studies increasing the potential success of the new drug candidate.
Administration
Transtympanic ( inner ear )
Intravitreal
Oral gavage ( per os )
Intravenous
Intraperitoneal
Intramuscular
Subcutaneous
Intranerve
Type of pharmacological
candidate
Molecules
Viral particles
Antibodies
Small proteins
Sampling
Cochlear perilymph
Vitreous and aqueous humor
Cerebrospinal fluid ( CSF )
Blood
Brain areas
Spinal cord
Organs and tissues
Bioanalysis
Immuno assay ELISA
HPLC
Mass spectrometry
Gene array
Protein array
Histological analysis

Example
Pharmacokinetic study of chemotherapy cisplatin in mice